The project QUOMPLEX authored by Mehul Malik (Coordinator), Pepijn Pinske and Claudio Conti is among the 26 excellent international proposals in the field of quantum technologies research recommended for funding in the QUANTERA call 2017, the first step of the Quantum Technologies flagship.
QUOMPLEX aims at harnessing random media, multi-modal propagation and machine learning for novel compact multi-level quantum gates.
The cascade of resonant -symmetric topological structures is shown to emit laser light with a frequency comb spectrum. We consider optically active topological lattices supporting edge modes at regularly spaced frequencies. When the amplified resonances in the PT-broken regime match the edge modes of the topological gratings, we predict the emission of discrete laser lines. A proper design enables the engineering of the spectral features for specific applications. Topological protection makes the system very well suited for a novel generation of compact frequency comb emitters for spectroscopy, metrology, and quantum information.
Graphene and Graphene oxide (GO) are capable of inducing stem cells differentiation into bone tissue with variable efficacy depending on reductive state of the material. Thus, modulation of osteogenic process and of bone mineral density distribution is theoretically possible by controlling the GO oxidative state. In this study, we laser-printed GO surfaces in order to obtain both a local photo-thermal GO reduction and the formation of nano-wrinkles along precise geometric pattern. Initially, after cells adhered on the surface, stem cells migrated and accumulated on the reduced and wrinkled surface. When the local density of the stem cells on the reduced stripes was high, cells started to proliferate and occupy the oxidized/flat area. The designed surfaces morphology guided stem cell orientation and the reduction accelerated differentiation. Furthermore the reduced sharp nano-wrinkles were able to enhance the GO antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), common cause of prosthetic joints infections. This strategy can offer a revolution in present and future trends of scaffolds design for regenerative medicine.