Exponential improvement in combinatorial optimization by hyperspins

Classical or quantum physical systems can simulate the Ising Hamiltonian for large-scale optimization and machine learning. However, devices such as quantum annealers and coherent Ising machines suffer an exponential drop in the probability of success in finite-size scaling. We show that by exploiting high dimensional embedding of the Ising Hamiltonian and subsequent dimensional annealing, the drop is counteracted by an exponential improvement in the performance. Our analysis relies on extensive statistics of the convergence dynamics by high-performance computing. We propose a realistic experimental implementation of the new annealing device by off-the-shelf coherent Ising machine technology. The hyperscaling heuristics can also be applied to other quantum or classical Ising machines by engineering nonlinear gain, loss, and non-local couplings.

Hyperscaling in the coherent hyperspin machine

https://arxiv.org/abs/2308.02329

Tsunami of light launched against 3D-printed tumor cells

Nature Communications 14, 4662 (2023)

Extreme waves are intense and unexpected wavepackets ubiquitous in complex systems. In optics, these rogue waves are promising as robust and noise-resistant beams for probing and manipulating the underlying material. Localizing large optical power is crucial especially in biomedical systems, where, however, extremely intense beams have not yet been observed. We here discover that tumor-cell spheroids manifest optical rogue waves when illuminated by randomly modulated laser beams. The intensity of light transmitted through bio-printed three-dimensional tumor models follows a signature Weibull statistical distribution, where extreme events correspond to spatially-localized optical modes propagating within the cell network. Experiments varying the input beam power and size indicate that the rogue waves have a nonlinear origin. We show that these nonlinear optical filaments form high-transmission channels with enhanced transmission. They deliver large optical power through the tumor spheroid, and can be exploited to achieve a local temperature increase controlled by the input wave shape. Our findings shed light on optical propagation in biological aggregates and demonstrate how nonlinear extreme event formation allows light concentration in deep tissues, paving the way to using rogue waves in biomedical applications, such as light-activated therapies.

Dark matter condensates as highly nonlocal solitons: instability in the Schwarzschild metric and laboratory analog

Theories on the bosonic nature of dark matter are a promising alternative to the cold dark matter model. Here we consider a dark matter halo in the state of a Bose-Einstein condensate, subject to the gravitation of a black hole. In the low energy limit, we bring together the general relativity in the Schwarzschild metric and the quantum description of the Bose-Einstein condensate. The model is solvable in the Fermi normal coordinates with the so called highly nonlocal approximation and describes tidal deformations in the condensate wave function. The black hole deforms the localized condensate until the attraction of the compact object overcomes the self-gravitation and destabilizes the solitonic dark matter. Moreover, the model can be implemented as a gravitational analog in the laboratory; the time-dependent potential generated by the galactic black hole can be mimicked by an optical trap acting on a conventional condensate. The results open the way to new laboratory simulators for quantum gravitational effects.

https://arxiv.org/abs/2305.10780

Parisi Nobel lecture mentioning our experiments

This is the extended version of the Giorgio Parisi Nobel lecture mentioning our experiments in nonlinear optics and random laser with the first observation of Replica Symmetry Breaking

https://arxiv.org/abs/2304.00580

See also Coloquio at the University of Pernambuco on youtube

See also Observation of replica symmetry breaking in disordered nonlinear wave propagation

See also The Experimental Observation of Replica Symmetry Breaking in Random Lasers

Launching optical tsunamis against tumor cells

We demonstrate the excitation of giant rogue waves of light inside human pancreatic tumor cells; they can be used for deep light transport and local heating for cancer treatment.

Rogue waves are intense and unexpected wavepackets ubiquitous in complex systems. In optics, they are promising as robust and noise-resistant beams for probing and manipulating the underlying material. Localizing large optical power is crucial, especially in biomedical systems, where extremely intense beams have not yet been observed. We here discover that tumor-cell spheroids manifest optical rogue waves when illuminated by randomly modulated laser beams. The intensity of light transmitted through bio-printed three-dimensional tumor models follows a signature Weibull statistical distribution, where extreme events correspond to spatially-localized optical modes propagating within the cell network. Experiments varying the input beam power and size indicate that rogue waves have a nonlinear origin. We show these optical filaments form high-transmission channels with enhanced transmission. They deliver large optical power through the tumor spheroid, which can be exploited to achieve a local temperature increase controlled by the input wave shape. Our findings shed new light on optical propagation in biological aggregates and demonstrate how extreme event formation allows light concentration in deep tissues, paving the way to using rogue waves in biomedical applications such as light-activated therapies

https://arxiv.org/abs/2303.04553